trepidation [ˌtrepɪˈdeɪʃn]

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n.惊恐，惶恐

fear or worry about what is going to happen

The men set off in fear and trepidation. 这群人惊慌失措地出发了。
The threat of an epidemic caused great alarm and trepidation. 流行病猖獗因而人心惶惶。