ruin [ˈru:ɪn]

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vt.（使）毁坏；（使）毁灭；n.(复)废墟；遗迹

to spoil or destroy severely or completely

How can you stand by and watch the country go to ruin? 你怎么可以看着国家将亡而无动于衷呢？
The old empty house soon went to rack and ruin. 这所旧的空房子很快就毁坏了。