estrange [ɪs'treɪndʒ]

以下由轻松背单词网站提供

vt.使疏远，离间，使离开

remove from customary environment or associations;

His behaviour estrange him from his brother. 他的行为使他与哥哥疏远了。
Madeleine was not trying to estrange her from the Herzogs. 马德琳无意要使她和赫索格家的人疏远。