depress [dɪˈpres]

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vt.使沮丧，使抑郁；使不景气；使萧条

to cause someone to feel unhappy and without hope for the future

The rainy days always depress me. 雨天总是使我沮丧。
Some medicines depress the action of the heart. 有些药物会减弱心脏的功能。